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Generic substitute for tamsulosin, a common synthetic opioid used for pain relief. But the new formulation is still too weak to compete with stronger alternatives. So for now, doctors and patients have little choice but to swallow pills that are more than 70 to 100 times weaker than the original. "It's just not very easy to get any other medication approved for opiates and other pain medications from FDA," said Dr. David Juurlink, director of the Centre for Drug Policy and Research at Sunnybrook Health Sciences Centre. "The reason the FDA is slow to approve drugs like morphine, fentanyl, is they've had a very difficult time getting drugs to be effective" against pain, Juurlink said. "They just don't have the evidence showing that this medication is effective." He said many doctors in his practice see patients who don't like taking prescription opioids. Many patients use the synthetic substitute to manage their pain, Juurlink said. "But people in my practices have told me they know that would feel more comfortable using a weaker medication that is more effective for their pain relief." Some doctors are taking the lead to help patients and reduce the number of harmful drugs currently available. The Ontario Association of Family Physicians has set up a list of more than 60 medications — including some that have been around for decades — that have had their approval reduced in the last two decades, including several that were previously approved for arthritis. The association says medications, which they have named the "Fentanyl-Related" Drugs, are effective for many what over the counter drugs are like xanax indications, including chronic pain, and do not pose risks to patients. But the association, which is made up mostly of family doctors in Ontario, is not pushing for a complete ban on the new drugs, which are in the process of being reviewed by the Canadian Food and Drug Regulations for approval. Many doctors are taking the lead to help patients and reduce the number of harmful drugs currently available. — Ontario Association of Family Physicians "We are not advocating for a complete ban," said Dr. Brian Day, medical director of the Centre for Integrative Pain Management at Ontario Women's College Health Sciences Centre, who helped compile the list of medications. "We don't think that everyone must be on all of them. We Xanax 2mg 180 $480.00 $2.67 $432.00 just see a need for more information." There are also concerns among some patients over the new drugs' short lifespan. Dr. Richard Stahl, vice-president of medical affairs and health education at Pain Care Canada, called on Health Canada to do something encourage more research on the new drugs that would better understand their efficacy. The new drugs' potency can vary widely. In some trials — those designed to test a new medicine — the potency of new opioids varied by 500 to 1,000 times, with fentanyl often dominating, Day said. He said the number of patients using drugs now is small, so doctors aren't seeing many new patients who are not already using them. "We are seeing a small number of patients at this stage their lives, who are starting to use the opioids, so we don't know what the longer-term safety profile is going to be," Day said. He said many patients feel the new prescription drugs are effective on pain relief. But doctors don't see the long-term effects of drugs, like addiction or the risk of overdose death, he said. Stahl added that believes the drugs are effective for some types of pain, but not for everyone. Dr. John Ronson, a family physician and assistant professor of obstetrics, gynecology and obstetrics at Dalhousie University in Halifax, said it's not possible to accurately compare the fentanyl and non-fentanyl opioids because they differ in terms of their potency. But while Ronson said research continues, he doesn't think the new opioid is that safe. "There's no question that there are some safety concerns because of over the counter drug like xanax the very small quantity that we know is in the pills," he said. "So we don't want to see any young people coming into the hospital and over the counter drugs that are like xanax dying of a fentanyl overdose." He said also doesn't think the new medicines offer enough therapeutic options to help people with long-term conditions. It's important to understand how quickly these new drugs come on the market, however, he said. "Because once they are on the marketplace, it's impossible to get them off of market very quickly. If we are looking to get a time where we are less dependent on these drugs, we have to be thinking about ways do that as soon they are legalized." The new drug has been shown to be highly addictive, and is considered as "highly dangerous" heroin. Day said he believes the new drugs can be better controlled by creating an entirely new category of drugs rather than banning them altogether. He also cautioned that there is.
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